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"On-X For Mitral Heart Valve Replacement?" Asks Vivian

Written By: Adam Pick, Patient Advocate, Author & Website Founder
Page Last Updated: May 12, 2025

Vivan has a severe mitral regurgitation and is preparing for mitral valve replacement operation. She is currently considering several different valve types including tissue valves and mechanical valve. Vivian's question to me is, "Adam - Can you tell me about the On-X valve for mitral valve replacement?"

For those of you who are not familiar with the On-X heart valve device for mitral replacement, here is some basic information for you:

On-X was founded in 1994 and is located in Austin, Texas. The company was later purchased by Artivion.
The On-X mitral valve is a carbon bileaflet heart valve prosthesis.
According to the Artivion website, the primary focus of the On-X mechanical valve replacement is that it was engineered for exceptional clinical performance, has optimal hemodynamics (mean gradients ≤ 4.4 mmHG across all valve sizes ≥ 25 mm reducing risk of PPM and has optimal length and leaflet guards designed to conceal pledgets, reduce risk of pannus and provide complete annular support when retaining subvalvular structure.
According to the company, over 50,000 On-X valves have been implanted since 1996.

I hope this give you some background on the On-X mechanical valve for mitral replacement surgery. Over the years, I have spoken with many patients that are happy with their selection of the On-X mitral valve. If you have an On-X replacement valve, please scroll below to leave a comment!

Keep on tickin!
Adam

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Written by Adam Pick
Patient & Website Founder

Written by Adam Pick - Patient & Website Founder

Adam Pick is a heart valve patient and author of The Patient's Guide To Heart Valve Surgery. In 2006, Adam founded HeartValveSurgery.com to educate and empower patients. This award-winning website has helped over 10 million people fight heart valve disease. Adam has been featured by the American Heart Association and Medical News Today.

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