Is Heart Failure Connected to Atrial Fibrillation & Mitral Valve Disease?

I just received a great question from Clay about mitral valve disease, atrial fibrillation and congestive heart failure.  In his note, Clay asked me, “Hi Adam, I have congestive heart failure and mitral valve prolapse plus long-term atrial fibrillation (AFib). My question is whether-or-not congestive heart failure is connected with mitral valve prolapse?  Thanks, Clay”



To answer Clay’s question, I reached out to Dr. Gorav Ailawadi who is the Chief of Cardiovascular Surgery at the University of Virginia Health System in Charlottesville, Virginia.  So you know, Dr. Ailawadi is a mitral valve and atrial fibrillation expert that is also the Surgical Director of the UVA Advanced Cardiac Valve Center.  I’ve been very fortunate to see Dr. Ailawadi perform a mitral valve procedure a few years ago.


Dr. Gorav Ailawadi (Heart Surgeon)


Dr. Ailawadi Says…

In response to Clay’s question, Dr. Ailawadi wrote:


This is an excellent question. The short answer is congestive heart failure is commonly associated and caused by mitral valve disease and atrial fibrillation (AF), but the answer is a bit more complex.  CHF, or congestive heart failure, is a syndrome where there is inadequate blood flow from the heart to the organs. This causes common symptoms of shortness of breath, fluid retention, and fatigue.  There are many causes of CHF including valve problems, weakened ventricular function (low ejection fraction), and coronary artery disease/ myocardial infarction.  We often consider it more of a symptom than anything else.

The mitral valve functions like two neighboring parachutes that open-and-close with each heart beat. Prolapse refers to the elongation of the cords of the valve (strings of the parachute).  Prolapse can lead to varying degrees of valve dysfunction but in its most severe form causes severe mitral regurgitation (MR), where blood leaks from the left ventricle back to the left atrium and lungs. This causes congestion in the lungs and also causes symptoms of CHF.

Finally, AF is often caused by severe mitral regurgitation because as blood leaks it causes extra stress, pressure, and volume in the left atrium. AF even by itself can lead to symptoms of fatigue and shortness of breath.



In the past, we would suggest a patient be considered for correction of severe MR from prolapse (usually with surgical mitral repair) when they develop AF or any symptoms. Recently, however, the guidelines have changed and have become even more aggressive and recommend surgery even in asymptomatic patients if the risk is low and mitral valve repair is highly likely at experienced centers.

To summarize, the congestive heart failure, mitral valve prolapse, and atrial fibrillation are usually, but not necessarily caused by each other. Hope this helps! — Dr. Ailawadi


Thanks Clay! Thanks Dr. Ailawadi!

I want to thank Clay for his excellent question and I would like to extend a special thanks to Dr. Ailawadi for sharing his research and clinical experiences with our patient community!  Dr. Ailawadi has been such a great supporter of our community over the years!

Keep on tickin!

Adam Pick
Written by Adam Pick

Adam Pick is a patient, author of The Patient's Guide To Heart Valve Surgery and the founder of

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