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Heart Murmur Issues With Loratadine And Aortic Stenosis?

Written By: Adam Pick, Patient Advocate, Author & Website Founder
Page Last Updated: June 12, 2025

I spent the first 33 years of my life with a heart murmur resulting from a congenital heart disorder known as a bicuspid aortic valve.

Now? After successful heart valve replacement surgery... Guess what? No more more heart murmur!

However, given my history, I am very sensitive to any questions I receive about heart murmurs. Although most murmurs do not results in heart valve surgery, some do. That said, taking preventative steps to minimize the risk of heart valve damage is critical.

Earlier today, I received an email about heart murmurs and loratadine. The questions read, "Can Loratadine cause a heart murmur?" and "Does Loratadine affect Aortic Stenosis?"

So you know, Loratadine is the generic name of popular antihistamine that is more readily known as Claritin. The product is made by Schering-Plough and is consumed in tablet or liquid form.

Intrigued and concerned by the possibility that Loratadine affects aortic stenosis and causes incremental heart valve damage, I did some quick research.

As for heart murmurs, loratadine, aortic stenosis and the possible complications of taking the drug, my research turned up very little clinical information.

However, at a very interesting site, RiskyBloodPressure.com, I learned some very interesting information. The site notes about Loratadine that, "Further testing is needed but it could be that Claritin may act as a vasoconstrictor, which means that the drug narrows blood vessels. If so, the drug can raise blood pressure in the body. If the blood flow in your system has already been compromised with conditions such as high cholesterol, heart disease and high blood pressure, Claritin should be avoided until you can seek further advice from your doctor."

Pretty interesting, right? What does that tell us? In my opinion, it tells me that you should chat with your cadiologist if you are taking Loratadine and you have a heart problem. Better safe than sorry.

Anyways, I hope that helps us all learn a little more about heart murmur, loratadine, and potential loratadine affects aortic stenosis.

Written by Adam Pick - Patient & Website Founder

Adam Pick is a heart valve patient and author of The Patient's Guide To Heart Valve Surgery. In 2006, Adam founded HeartValveSurgery.com to educate and empower patients. This award-winning website has helped over 10 million people fight heart valve disease. Adam has been featured by the American Heart Association and Medical News Today.

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