Pulmonary Valve Regurgitation
Written By: Adam Pick, Patient Advocate, Author & Website Founder
Page Last Updated: May 14, 2025
Pulmonary regurgitation is an incredibly common condition – in fact, up  to 90 percent of Americans have some form of it, according to the  Children's Heart Specialists of Kentucky.
That said, most people don't show any symptoms of pulmonary regurgitation and don't need any type of treatment. Severe cases, though, require regular monitoring, medications to relieve symptoms and even surgery to insert an artificial valve or tube.
What is Pulmonary Valve Regurgitation?
Pulmonary regurgitation occurs when the pulmonary valve in the heart  doesn't operate properly. During a regular heartbeat, the lower right  chamber of the heart, called the right ventricle, pushes blood through  the pulmonary artery into the lungs. If the valve in the pulmonary  artery doesn't close completely, blood can leak back from lungs into the  heart between heartbeats.
 
 Most people don't exhibit symptoms of pulmonary regurgitation, and  infants or children born with the condition typically don't show signs of it until  they are older. Many of the more severe cases of the disorder appear in  people who have had heart surgery to insert an artificial conduit  between the right ventricle and pulmonary artery. People who do exhibit  symptoms often have a severe form of this condition.
What are the Symptoms of Pulmonary Valve Regurgitation?
Patients with a serious case of pulmonary regurgitation may experience the following symptoms:
- Fatigue
 - Difficulty breathing, especially when exercising or engaging in other intense physical activity
 - Fainting or dizziness
 - Heart murmur
 - Arrhythmia
 - Palpitations, or rapid or irregular heartbeats
 - Chest pain, including pressure, squeezing and tightness
 - Swelling in the feet or legs
 - Bluish lips or nails
 
How is Pulmonary Valve Regurgitation Diagnosed?
Doctors are often keyed into the possibility that a patient might have  pulmonary regurgitation if they notice abnormal sounds in the chest, an  enlarged liver, fluid retained in the ankles or a distended jugular vein  in the neck.
 
 While doctors begin a diagnosis by checking a patient's symptoms, medical history and performing a physical exam, certain tests must be  done to confirm pulmonary regurgitation. It can be revealed through a  chest X-ray; a cardiac MRI, which creates a 3D image of a heart; an  echocardiogram, which uses sounds waves to map the heart; or an  electrocardiogram, which records the heart's electrical activity. Other  diagnostic methods include pulse oximetry, which painlessly monitors  oxygen levels in blood, and cardiac catheterization, in which a thin  tube is guided into the leg or belly button and through a blood vessel  into the heart.
How is Pulmonary Regurgitation Treated?
Trivial cases of pulmonary regurgitation do not require immediate treatment, and some doctors feel that these cases don't even need regular checkups. Moderate or severe pulmonary regurgitation, though, needs monitoring, and if it worsens, surgery might be necessary.
Currently, there are no medications that treat the root problem of pulmonary regurgitation, but  some drugs can alleviate its symptoms and help the heart beat more  normally. These medicines are often diuretics that flush extra water  from the body or drugs that help hearts beat more regularly in  conditions such as palpitations and arrhythmia.
 
 In severe cases, doctors might determine that the valve needs to be  replaced or repaired and its function improved through a surgical  procedure called valvuloplasty. At this point, a patient's options  include having the pulmonary valve removed and replaced with a new one  or having an artificial conduit placed between the pulmonary artery and  right ventricle.
Melody Pulmonary Valve Replacement 
One of the newest types of valves, the Melody valve, is a transcatheter procedure that does not cause any trauma to the patient's chest or ribs. Instead, the valve is put into a patient through a  catheter in a leg blood vessel. For children, one of the best choices is  a pulmonary homograft. This donated pulmonary valve and artery can grow  with the child.
 
 In the future, doctors might be able to harvest a patient's cells and  use them to grow a new valve on a biodegradable mesh. This treatment is  still being worked on and isn't performed yet. 
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