Surgeon Spotlight: Dr. Chris Malaisrie

Northwestern Medicine, Chicago, Illinois - Sponsored Post

As a heart surgeon at Chicago’s Bluhm Cardiovascular Institute at Northwestern Memorial Hospital, S. Chris Malaisrie, MD, is accustomed to performing surgery in the O.R. every day. But he never forgets there is something new to learn with each operation.

"Heart surgery is a truly enjoyable experience," states Dr. Malaisrie. "To put someone's circulation on a machine - to maintain their circulation in an artificial circuit, and operate on its internal structures - is an incredible technical feat, and an enormous responsibility."


Dr. Chris Malaisrie - Heart Surgeon at Northwestern Medicine


“I have been part of Northwestern Memorial Hospital for over a decade,” states Dr. Malaisrie. As associate director for Bluhm Cardiovascular Institute’s Center for Heart Valve Disease and co-director of its Thoracic Aortic Surgery Program, Malaisrie maintains an intense focus on heart valve research and elevating industry best practices.

“Technology to help us accomplish these less-invasive surgical feats is advancing rapidly,” he says. “This lightning-fast development of new technologies is a key step in bringing new techniques, safely to the forefront.”


A personal experience with surgery

The seed of interest in surgery was planted early in Malaisrie: His father was a general surgeon in Baltimore, Maryland, where Malaisrie was raised. “My father was very good at not bringing work home, but we knew when he got called at home that it was something vitally important.”

Malaisrie’s interest in medicine truly blossomed when he developed appendicitis in elementary school. “My father diagnosed me, but he didn’t perform the surgery,” he explains. “My father was a role model for my future work. When I got sick, he instilled confidence in me during a very frightening moment, and that’s the kind of confidence we heart surgeons want to instill in our patients, our colleagues and co-workers. I learned that from my father.”


The path to Chicago

Malaisrie graduated from the University of Maryland School of Medicine in 1998. He completed his residency at Loyola University Medical Center in 2004, and multiple fellowships at Baylor College of Medicine and Stanford Hospital and Clinics.

He came to call Chicago home when he joined Northwestern Memorial Hospital in 2007. In addition to his other roles, Malaisrie is a member of the Northwestern Medical Faculty Foundation and an associate professor at Northwestern University Feinberg School of Medicine. He is board certified by both the American Board of Surgery and the American Board of Thoracic Surgery.


Innovating and inspiring at Northwestern Memorial

Malaisrie has grown a reputation that brings patients from across the country to see him. His intense interest in bicuspid aortic valve treatment, aortic aneurysms and aortic dissections has led him to participate in numerous national research efforts. He also focuses on Marfan syndrome and related connective tissue disorders.


Dr. S. Chris Malaisrie in Operating Room  

In addition to the full spectrum of cardiac surgery, Malaisrie performs valve-sparing aortic root replacements, aortic arch reconstruction, thoracoabdominal aortic repair and endovascular stent grafting. A big focus of his work is on development and perfection of minimally invasive valve procedures for patients, such as transcatheter procedures for the aortic valve (transcatheter aortic valve replacement, or TAVR) and mitral valve (transcatheter mitral valve replacement or TMVR).

“Right now about 20% of cardiac surgeons perform minimally invasive procedures,” says Malaisrie. “I believe we’re seeing an evolution that will make these procedures much more the norm. They offer easier recovery, less pain, and better cosmetic results—and while they are as safe as standard cardiac surgery, they may be associated with better outcomes. And that’s what I want for my patients.”


Research and teaching to reinforce experience

“Leading and participating in research efforts is another essential step in advancing cardiac surgery, one I’m very enthusiastic about,” explains Malaisrie. “Part of advancing the field of cardiac surgery is teaching others,” Malaisrie adds. “I work with medical students on cardiac surgery rotation, and train residents so they leave our program armed with the skills they need to become great cardiac surgeons. It’s one of the things I love about my work with Northwestern.”

Malaisrie is currently involved in eight research projects related to heart valve disease:

  1. A Prospective, Single-Arm, Multicenter Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients With a Failing Aortic Bioprosthetic Valve
  2. Evaluation of the Thoraflex™ Hybrid Device for Use in the Repair or Replacement of the Ascending Aorta, Aortic Arch and Descending Aorta in an Open Surgical Procedure. Protocol #: Hybrid-002
  3. A Prospective, Multicenter, Non-Blinded, Non-Randomized Study of the RelayPro Thoracic Stent-Graft in Subjects with an Acute, Complicated Type B Aortic Dissection
  4. Early Feasibility Study of the CardiAQ™ Transcatheter Mitral Valve Implantation (TMVI) System (Transseptal and Transapical Delivery Systems) For the Treatment of Moderate to Severe Mitral Regurgitation
  5. Annular ReduCtion for Transcatheter Treatment of Insufficient Mitral ValvE (ACTIVE): A prospective, multicenter, randomized, controlled pivotal trial to assess transcatheter mitral valve repair with Edwards Cardioband system and guideline directed medical therapy (GDMT) compared to GDMT alone in patients with functional mitral regurgitation (FMR) and heart failure
  6. Prospective, Multicenter, Multidisciplinary, Controlled Clinical Investigation Evaluating the Safety and Efficacy of PerClot® Polysaccharide: The C.L.O.T. Investigation System
  7. A Prospective, Randomized, Controlled, Multi-Center Study to Establish the Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients who have Severe, Calcific, Aortic Stenosis Requiring Aortic Valve Replacement
  8. Aortic Valve Operative Outcomes in Marfan Patients


On his days off

Malaisrie lives with his wife and three children in Chicago’s Lincoln Park neighborhood. He plays classical piano, and his kids are all learning musical instruments, too. As a family, they love to soak in all that the city has to offer.

“Chicago’s a great international town, packed with restaurants, parks and culture that our whole family loves,” he says. “Plus it’s a hub, so it’s easy to get anywhere else in the world.”

That geographic desirability is ideal for Malaisrie, who is also a philanthropist in his family’s native country of Thailand. As president-elect of the Thai Physicians Association of America, he spends much of his free time raising funds for hospitals and schools on the other side of the globe.

“Many Thai hospitals are in need of very, very basic things,” he says. “Fundraising is a hard job, but I’m very glad—and grateful—to be able to help.” He loves to travel there with his family, exploring their heritage and making a difference in the lives of others.

It’s all part of Malaisrie’s lifelong mission to help others. “When a patient comes to me in need of help, it’s a huge thing, an incredible thing, to be able to change their life,” he says. “I want to always ensure I am doing the best work I can to help advance my field and offer the best care to my patients, while teaching others to do the same. It’s very gratifying work.”


Page last updated: September 17, 2020