About Dr. Mario Castillo-Sang,
Heart Surgeon

"Dr. Castillo-Sang has been wonderful from the first time we met him. He is a wonderful teacher, educator as well as very personable and obviously a skilled surgeon.
He was highly recommended by more than one source outside of the St. Elizabeth Healthcare system and has met every expectation."

"Dr. Castillo-Sang has been a blessing to my life and my family's life. From initially consulting with him in October 2025, to numerous scans, tests, and hour-long meetings with him into 2026, he honestly has been and is the most passionate and efficient surgeon and/or doctor I have ever witnessed. From his office to surgery to recovery, I wouldn't want my health in anyone else's hands. He and his staff at St. Elizabeth Edgewood are true Godsends! Thank you Dr. Castillo-Sang for everything!"

"This surgeon is amazing, No pain after surgery. I am impressed with his bedside manner and the way he treats his patients. I would recommend him to anyone."

"Dr. Castillo-Sang takes time to make sure you understand what is going on. I feel great after surgery. Better than I've felt in a long time."

"Dr. Castillo-Sang is an amazing surgeon. He's easy to talk to and explains everything throughly. The surgery went smoothly. He came and spoke to our family after the surgery. I would refer him to anyone looking for a cardiac surgeon to use. We also loved working with his staff in the office. 100 percent would use again."

"Dr. Castillo-Sang was an amazing doctor. He is very kind and helpful his bedside manner is wonderful. He and his staff were very attentive and professional. They seemed to really care about my health and making sure that everything heals perfectly. I believe Dr Castillo-Sang saved my life we will always be grateful for his help."

"This doctor saved my life! Ten days after surgery, I feel better than I have felt in five to six years. He truly cares and wants to help people. I could not be any happier that he was my surgeon.

I highly recommend him and his team at St. Elizabeth in Edgewood! Thank you for all that you have done, Dr. Castillo-Sang! You are truly one in a million!"

"Great! There is not enough good things to say about Dr. Castillo-Sang. He was very professional and has the best staff of professionals under him. I was very well taken care of. I would recommend him to anyone. No doubt the best! On a ccale of 1-10. He is definitely a 10. Thank you so much for all your support!"

"I'm glad Dr. Castillo-Sang was my surgeon. He explained everything to my family in a way that I wasn't worried as much. He kept them informed of every aspect of the surgery. Videos and images aplenty."

"Dr. Castillo-Sang and his care was beyond my wildest expectations!

I immediately felt at ease with him from the first moment he entered my room. His bright smile to his warm handshake put me at ease. And then he spoke with such caring, respect and confidence that I immediately trusted him. On my way to surgery I was afraid I have to admit but my fear wasn't that I didn't trust him or his incredible staff it was that my body would fail.

I feel blessed that on a weekend away from home I found my way to Dr Mario. It had to be serendipity. Thank you all for taking such good care of me. God bless you all."

"Dr. Castillo-Sang gave such peace of mind. His bedside manner is fantastic and he was so knowledgeable and caring!"

"Great. I'm very happy and I'm feeling better already. Thank you."

"Very good experience, happy with the results as everything seems to be going as expected. Dr. Castillo-Sang was very honest. He answered all questions."

"Understanding, very trustworthy. Exceptional customer care and support."

"Dr. Mario is absolutely wonderful! His knowledge is superior in his field. He was excellent at sharing knowledge with us before and after the surgery. He is kind, caring and very thoughtful! Because of his skillful hands my recovery was flawless.

I am so thankful that he came into my life and I will be forever in his debt. Praises also for the surgical team, the nurses and all the staff who worked with us. We had no bad experiences with anything."

"Dr. Mario was wonderful in all respects - great bedside manner, extremely professional, caring and excellent personality. Dr. Mario is one of the best. He is a great surgeon."

"I had a good experience. Good bedside manner. Surgical results: well, I'm not dead! 🤣 Thanks for that!"

"Dr. Castillo-Sang was awesome and after three weeks I was ready to resume my normal life activities."

"Awesome! Very professional, kind and explained everything thoroughly."

"Thorough, evidence based and effective. Detailed explanations were provided about what the heart problems are and how to repair them."

"Dr. Castillo-Sang is a great surgeon."

"Dr. Castillo-Sang is a wonderful surgeon. He explains the problem and procedures quite well. Very courteous and friendly at all times.

Excellent results from surgery, now with a properly functioning heart. Through Dr. Castillo-Sang, my stress level was minimal and knowledge about my heart function was greatly increased.

I'm extremely happy and grateful for the whole experience."

"Excellent. I couldn't have a better experience! I feel so much better."

"Dr Castillo-Sang was phenomenal! I had complications due to previous health issues and his after care was more than I could have imagined. At my post-op appt, I am now living with a repaired mitral valve, no murmur and no blockages. No doubt this wonderful surgeon saved my life!"

"From start to finish, my experience with Dr. Castillo-Sang could simply have not been better! He was super caring and informative on all matters and did a wonderful job on my surgery.! Five stars out of 5 for sure…. My highest recommendation for anyone needing heart valve surgery!"

"The best doctor and team - both in the office and in the hospital. God bless them all. They saved my life!"

"My experience with Dr Castillo-Sang was wonderful. I had complete peace going into the surgery because of his confidence and reassurance of a successful outcome. I couldn't recommend him or his nurse practitioner, Julie, more!"

"Amazing! Dr. Castillo-Sang's bedside manner is top-notch, first class. His whole team from pre-op to post-op to recovery to ICU to office support -- all these folks were amazing. Took so much anxiety away. The place to go for Heart and Vascular is St. Elizabeth. Thank you!"

"Dr. Mario explained everything throughly and answered multiple questions we had. His compassion for his job is superior and the empathy he has for his patients is first class. Each appointment with him has been a wonderful experience. We look forward to many heart healthy years due to his excellent care!!"

"Dr Castillo-Sang was exceptional. From my first meeting with him, he put me at ease. He explained the procedure, so I knew what to expect.

My hospital experience went very smoothly. He stopped-in briefly each day to check on me and answer any questions I might have. He always had a smile and a moment to chat. My family enjoyed his visits as well.

I feel very lucky to have Dr Castillo-Sang as my surgeon. He is a valuable asset to St. Elizabeth Hospital."

"Dr. Castillo-Sang was very knowledgeable and down to earth. He treated me like a person not just a patient. He is a great surgeon."

"My experience has been wonderful."

"This was initially an overwhelming experience, but Dr. Castillo-Sang has been extremely supportive, professional, and reassuring every step of the way.

At our first meeting, I could tell he loves what he does, which really calmed me. And his illustrations helped as well. Every single nurse, staff member I've met during this whole process has been WONDERFUL.

I couldn't have asked to be in better hands and am grateful for all the care and kindness I received. Thank you for such a positive experience."

"Dr. Castillo-Sang was thorough and engaging. He was compassionate and kind. He answered all my questions. He took very good care of me."

"Loved my experience with Dr. Castillo-Sang. He also kept me informed on my care."

"Absolutely excellent. I am so impressed with Dr. Castillo-Sang's ability to make me feel special and cared for."

"Amazing. Very professional caring experience. So glad and fortunate that we were able to find such a professional team."

"Dr. Castillo-Sang was a great surgeon and took great care of me. My wife was admitted at the same time as I was and the staffing took me to see her anytime I wanted to. He did a fantastic job with my heart. He allowed me extra time there to spend with my wife."

"Dr. Castillo-Sang was awesome through everything."

"Very informative doctor. Dr. Castillo-Sang was willing to take the time to make sure I was comfortable with understanding my condition/procedure. Would very highly recommend this doctor to anyone in need."

"Dr. Castillo-Sang was very clear from the beginning of the procedure and the steps pre- and post-op. I will be recommending Dr. Castillo-Sang to anyone needing a mitral valve repair."

"Dr. Castillo-Sang was very thorough and informative."

"Wonderful experience from Dr. Castillo-Sang to all the nurses."

"Very kind and patient. We were extremely pleased with the surgery outcome and feel lucky to have Dr. Castillo-Sang and his entire team care for us."

"Dr. Mario Castillo-Sang was excellent. The nurses were very helpful and my recovery has been better than I expected. My surgery was on Monday and I was home by noon on Thursday. Now, at 10 days after surgery, I have no pain and feel almost back to normal."

"Absolutely phenomenal! Dr. Castillo-Sang is the kindest and most caring surgeon I have ever had the pleasure of knowing or having worked on me. I wouldn't ever want anyone else."

"He was my savior. He's excellent. He saved my life."

"Best experience I could have asked for. The doctor was very patient and friendly, as well as extremely knowledgeable. I don't have anything but amazing things to say about both the doctor and staff."

"Absolutely amazing!!!!!!!! Dr. Castillo-Sang has wonderful bedside manners and did an amazing job explaining the procedure."

"I feel truly blessed to have had my procedure done by Dr. Castillo-Sang and his group of caring professionals.

I am an older patient and he explained the need for the surgery and all the pros and cons. I was never rushed but felt informed and that I had made the right decision. The pre-op procedure was professional and easy to understand. I had the under arm procedure and had a little discomfort but really no significant pain. All the team professionals introduced themselves and were there for me throughout.

Dr. Castillo-Sang visited me and my family several times post-op. The visits were not hurried but gave full information about plans going forward.

I cannot say enough about my high quality of professional care that was always given with kindness. Dr. Castillo-Sang and his team are an asset to the Northern Kentucky medical community."

"Outstanding! Dr. Castillo-Sang gave me my life back. Gifted surgeon."

"Dr. Castillo-Sang has been wonderful to work with. He is always pleasant and patient with all of our questions. He did an excellent job on the surgery. Everything went as planned and my valve was repaired. Thank you Dr. Castillo-Sang!"

"Experience was amazing. Mario explains everything very well and the care was perfect. I ask a lot of questions about which valve to use. He was always willing to answer my questions and is always willing to help you.

After having my mitral valve replaced, the hospital stay was very short. Nurses were very helpful. Everything went great.

Saint Elizabeth, thanks so much for taking good care of me."

"I feel truly blessed to have had my procedure done by Dr. Sang and his group of caring professionals. I am an older patient and he explained the need for the surgery and all the pros and cons.

I was never rushed but felt informed and that I had made the right decision. The pre-op procedure was professional and easy to understand. I had the under arm procedure and had a little discomfort but really no significant pain. All the team professionals introduced themselves and were there for me throughout.

Dr. Castillo-Sang visited me and my family several times post-op. The visits were not hurried but gave full information about plans going forward.I cannot say enough about my high quality of professional care that was always given with kindness.

Dr. Castillo-Sang and his team are an asset to the Northern Kentucky medical community."

"Dr. Castillo-Sang was amazing. It was the best experience ever. Bedside manner was great. Treatment was what everyone hopes for with their doctor."

"Excellent experience with Dr. Castillo-Sang. Very personable. The doctor takes the time to explain and make sure patients/family understand. Patients don't feel rushed during appointments or at bedside.

Surgery day couldn't have run better. Regular updates through surgery and available after as well. Dr. Castillo-Sang is meticulous with bedside care during admission."

"Excellent surgeon. Explained everything well. Would recommend Dr. Castillo-Sang to anyone. Glad I got to have him on my side."

"I would definitely recommend Dr. Castillo-Sang. He is personable, answers any questions you may have, and explains the procedures carefully. You are in good hands with him and his team. His staff is also good to work with. Of course, I was his favorite patient."

"Dr. Castillo-Sang was great throughout the whole process. He thoroughly explained the procedure and the options going into surgery. He was there post-op to continuously monitor my status and that I was getting whatever I needed.

He always took the time to explain and/or answer all of our questions in the hospital and at the post-op appointment.

I am feeling great and I am up and getting around and it's been less than two weeks. So, I am very excited with the results."

"GREAT! I am extremely thankful for Dr. Castillo-Sang."

"Absolutely amazing! I would recommend Dr. Castillo-Sang to everyone!"

"Wonderful service! Dr. Mario Castillo-Sang is a great surgeon. I would recommend him to anyone. I have my life back. At 69 years old, I feel like I'm 40. LOL!

His team and nurses all play a big part in recovery. Thanks!"

"Dr. Castillo Sing was excellent. He was patient and answered all my questions pre-surgery. After surgery, he was equally superb. He is personable and compassionate. I owe him enormous gratitude for my level of care."

"Dr. Castillo-Sang was very thorough in explaining the procedure before and after surgery. He was very patient with us throughout the process. Surgery was minimally invasive and recovery has been relatively easy."

"I am so very grateful to Dr. Castillo-Sang for the wonderful "second chance at life" he has given me!

The level of care has been amazing along with the excellent results of the surgery. His heartfelt compassion was obvious with everything he did! Thank you so very much, Dr. Castillo-Sang!"

"Outstanding! Dr. Castillo-Sang truly cares and made sure I understood everything along the way."

"Dr. Castillo-Sang exceeds all expectations. He is very caring and personable. He connected with me and treated me as if I was his father. I would recommend him to anyone looking for cardiac surgeon."

"Excellent. Treated with a sense of urgency. I felt confident in his and the teams ability and knowledge."

"Wonderful caring doctor with great people skills. Very informative and patient."

"Dr. Castillo-Sang was very thorough in explaining every aspect of the transcatheter mitral valve repair (TMVR). I was immediately set at ease by his knowledge and passion for his work. He was the most personable and accessible doctor that I have ever met.

All of staff I encountered while under his care also spoke very highly of him. My surgery went exceptionally well and without any complications. I feel so very grateful to have had him as my surgeon and I am very much looking forward to enjoying life with new energy."

"My experience with Dr. Mario Castillo-Sang greatly exceeded every expectation I had in a surgeon. Dr. Castillo-Sang is an extremely warm and personable man who shows great skill and passion for his work. He made sure I was completely informed every step of way and that I was given the best care possible. His compassion and accessibility is unmatched and I felt very confident that I was in the best hand.

My surgery went as expected and without complications. I was amazed at how small the incision was and how quickly I was back on my feet. He stayed involved and showed concern every step of the way and continues to show great support and care one year later.

I wish that everyone could have him as their surgeon and receive such phenomenal care. I am eternally grateful to have him as my surgeon."

"My experience has been wonderful! Everyone has been very knowledgeable and encouraging in my recuperation! Everyone has been kind and very professional! Would definitely recommend their care!"

"Dr. Castillo-Sang is an amazing surgeon. He did a wonderful job and I feel great. He has been wonderful. I would highly recommend."

"Dr. Castillo-Sang's care before-and-after surgery went far beyond what can be expected. I knew in my first discussion with him that he was a compassionate person. He often checked on me in the hospital. Follow-up visits are very pleasant and thorough. He takes good care of me and I am grateful he is my doctor."

"I love my surgeon. He explained everything to me beforehand. He and his staff take great care of my heart. They are kind and considerate and compassionate."

"Dr. Mario Castillo-Sang, Thank you for your professional care, your knowledge and skill! Thank you for giving me a better heart and a chance to live a healthier life!

My family and I thank you and your professional medical team and your personal concerns and medical skills. I will refer you and your team to anyone in need of cardiac medical care. My heart is healthier because of you, Dr. Mario Castillo-Sang!"

"Dr. Sang, who I call "Super Mario", saved my life. Not only did he save my life but his minimally-invasive technique saved me months of recovery time.

Originally, he thought there were 3 tears in my mitral valve. There ended up being 11 and there was a small hole in my heart. Once he found that out, he reassessed the situation and decided he could still do the repair instead of having to replace my valve.

When I met him the first time, he spent 45 minutes with my wife and me. He explained everything to us and answered all of our questions. He has a great bedside manner! I highly recommend him to anyone needing heart surgery."

"Doctor Sang was extremely helpful in explaining my procedure in a language that I could understand. He provided the most optimistic outlook for my surgery and future expectations of my overall health and well being. I appreciate the confidence he instilled in me and my family thank you!"

"Very smooth process, very professional and explained procedures thoroughly. Hospital stay to be as expected, no issues or complaints."

"Excellent, could not have gone better!!!"

"Dr. Castillo-Sang's bedside matter is very kind and his surgical results were incredible. He explained difficult technical information to us in a way that we were able to understand. He also displayed confidence and expertise that helped to comfort us.

He is brilliant, empathetic and kind. I will be grateful for Dr. Castillo-Sang for the rest of my long happy life!"

"I loved Dr. Mario! Not only was my surgery successful with a relatively easy recovery and minimal scaring, but my surgeon had awesome bedside manner, was extremely caring, and was always available for any follow up questions or care, both while in the hospital and after discharge. I highly recommend Dr. Mario to anyone that needs this type of surgery."

"I can not express what a wonderful doctor and human being Dr. Castillo-Sang is. He has always treated me with kindness and concern. Dr. Castillo-Sang really listened to me which I appreciated. My surgery went without any concerns. Dr. Castillo-Sang kept me in the loop explaining the why's and the how's. I highly recommend Dr. Castillo-Sang to anyone, which I already do."

"When first diagnosed in hospital, the Head of the Cardiac department recommended that surgery had a very high risk of death (based on being 80 years old) and the hospital would not allow an operation to repair or fix my mitral valve. After further consultation with my heart doctor, he recommended Dr. Castillo-Sang be consulted.

Dr. Castillo-Sang reviewed my records and agreed to perform the operation. He performed a non invasive open heart surgery and replaced my mitral valve. The surgery went well and was accomplished with out breaking any bones. The surgery was even accomplished without me needing to take any pain medicine. Dr. Castillo-Sang closely followed my recovery from surgery and kept me fully informed as to my progress and what I needed to do after release from the hospital. In addition, he is a really nice and caring person. He made me feel secure during the entire process.

Dr. Castillo-Sang is a gifted and caring surgeon who is constantly trying to improve the methods and techniques to lower the risk of surgery and also to make the operation less intrusive on the patients body.

What a great Doctor and Surgeon. I highly, highly recommend contacting Dr. Mario Castillo-Sang if you ever need the replacement of your mitral valve."