About Dr. Mario Castillo-Sang,
Heart Valve Surgeon

Hello! My name is Dr. Mario Castillo-Sang and I am a cardiac surgeon having graduated from Escuela de Medicina Ignacio A Santos in 2004. St. Elizabeth Healthcare performs approximately 600 heart surgeries each year. All St. Elizabeth Healthcare cardiac surgeons complete between 125-150 cardiac cases per year. Read more...

30 Patient Reviews for
Dr. Castillo-Sang

"Dr. Castillo-Sang has been wonderful to work with. He is always pleasant and patient with all of our questions. He did an excellent job on the surgery. Everything went as planned and my valve was repaired. Thank you Dr. Castillo-Sang!"

-- Bruce Hartman, Mitral Valve, Valve Repair, 07/08/2025

"Experience was amazing. Mario explains everything very well and the care was perfect. I ask a lot of questions about which valve to use. He was always willing to answer my questions and is always willing to help you.

After having my mitral valve replaced, the hospital stay was very short. Nurses were very helpful. Everything went great.

Saint Elizabeth, thanks so much for taking good care of me."

-- David Tebbing, Mitral Valve, Valve Replacement, 07/07/2025

> See 28 more patient testimonials

My Specialities &
Clinical Interests

My heart surgery specialties include:

  • Minimally invasive mitral valve surgery using endoscopic techniques
  • Atrial fibrillation (Maze procedure)
  • Transcatheter valve therapy including TAVR

In addition, I have research and clinical interests specific to:

  • Ventricular contractility in Barlow's mitral valve disease and in bileaflet prolapse
  • Coronary revascularization
  • Mitral valve imaging

Education, Training & Certificates

Dr. Mario Castillo-Sang, heart surgeon, graduated from Escuela de Medicina Ignacio A Santos in 2004.

After medical school, Dr. Castillo-Sang completed a general surgery residency at University of Toledo College of Medicine in 2010. Next, he completed a cardiothoracic surgery fellowship at Washington University Barnes Jewish Hospital in 2012.

Dr. Castillo-Sang is a nationally-recognized heart valve expert that practices in Kentucky. He specializes in minimally-invasive mitral valve repair surgery using endoscopic techniques.

Dr. Castillo-Sang is board certified by the American Board of Thoracic Surgery. Dr. Castillo-Sang has earned a spot on Cincinnati Magazine's "Top Doctors".

Schedule Appointment
with Dr. Mario Castillo-Sang, MD

To schedule an appointment with Dr. Castillo-Sang, you can:

The office of Dr. Castillo-Sang is located at 711 Medical Village Drive, Suite 310, Edgewood, KY 41017. To get driving directions to this office, please click the map below.



> Click for driving directions to Dr. Castillo-Sang’s office.

News & Online References Featuring Dr. Mario Castillo-Sang

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Page last updated: July 17, 2025