About Dr. Mario Castillo-Sang,
Heart Valve Surgeon

Hello! My name is Dr. Mario Castillo-Sang and I am a cardiac surgeon having graduated from Escuela de Medicina Ignacio A Santos in 2004. St. Elizabeth Healthcare performs approximately 600 heart surgeries each year. All St. Elizabeth Healthcare cardiac surgeons complete between 125-150 cardiac cases per year. Read more...

25 Patient Reviews for
Dr. Castillo-Sang

"Dr. Castillo-Sang was great throughout the whole process. He thoroughly explained the procedure and the options going into surgery. He was there post-op to continuously monitor my status and that I was getting whatever I needed.

He always took the time to explain and/or answer all of our questions in the hospital and at the post-op appointment.

I am feeling great and I am up and getting around and it’s been less than two weeks. So, I am very excited with the results."

-- Mary McCann, Mitral Valve, Valve Replacement, 05/05/2025

"GREAT! I am extremely thankful for Dr. Castillo-Sang."

-- Connie Berndsen, Mitral Valve, Valve Repair, MitraClip, 05/02/2025

> See 23 more patient testimonials

My Specialities &
Clinical Interests

My heart surgery specialties include:

  • Minimally invasive mitral valve surgery using endoscopic techniques
  • Atrial fibrillation (Maze procedure)
  • Transcatheter valve therapy including TAVR

In addition, I have research and clinical interests specific to:

  • Ventricular contractility in Barlow's mitral valve disease and in bileaflet prolapse
  • Coronary revascularization
  • Mitral valve imaging

Education, Training & Certificates

Dr. Mario Castillo-Sang, heart surgeon, graduated from Escuela de Medicina Ignacio A Santos in 2004.

After medical school, Dr. Castillo-Sang completed a general surgery residency at University of Toledo College of Medicine in 2010. Next, he completed a cardiothoracic surgery fellowship at Washington University Barnes Jewish Hospital in 2012.

Dr. Castillo-Sang is a nationally-recognized heart valve expert that practices in Kentucky. He specializes in minimally-invasive mitral valve repair surgery using endoscopic techniques.

Dr. Castillo-Sang is board certified by the American Board of Thoracic Surgery. Dr. Castillo-Sang has earned a spot on Cincinnati Magazine's "Top Doctors".

Schedule Appointment
with Dr. Mario Castillo-Sang, MD

To schedule an appointment with Dr. Castillo-Sang, you can:

The office of Dr. Castillo-Sang is located at 711 Medical Village Drive, Suite 310, Edgewood, KY 41017. To get driving directions to this office, please click the map below.



> Click for driving directions to Dr. Castillo-Sang’s office.

News & Online References Featuring Dr. Mario Castillo-Sang

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Page last updated: May 15, 2025