{"id":1343,"date":"2010-07-14T08:04:13","date_gmt":"2010-07-14T13:04:13","guid":{"rendered":"http:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/?p=1343"},"modified":"2025-06-24T03:45:46","modified_gmt":"2025-06-24T08:45:46","slug":"dr-saibal-kar-alfredo-trento-mitraclip-cedars-sinai","status":"publish","type":"post","link":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/2010\/07\/14\/dr-saibal-kar-alfredo-trento-mitraclip-cedars-sinai\/","title":{"rendered":"Cardiac Clinic Tour: Dr. Kar and Dr. Trento Join Forces In MitraClip Study at Cedars-Sinai Hospital"},"content":{"rendered":"<p>Recently, I was extremely lucky to observe Dr. Saibal Kar and his team perform its 103rd MitraClip procedure on a patient with severe mitral regurgitation at Cedars-Sinai Hospital in Los Angeles, California.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\" aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/dr-saibal-kar-adam-pick.jpg\" alt=\"Dr. Saibal Kar and Adam Pick At Cedars-Sinai Hospital\" width=\"350\" height=\"231\" \/>Dr. Saibal Kar And Me In The Cath Lab At Cedars-Sinai<strong><br \/>\n<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p>While I expected to watch the procedure from a gallery \u2013 much like an episode of <em>Grey\u2019s Anatomy<\/em> \u2013 I quickly found myself inside the cardiac catheter lab wearing scrubs and a lead suit used to protect me against x-ray exposure from fluoroscopy.<\/p>\n<p>For the next three hours, I had front-row access to Dr. Saibal Kar&#8217;s team as they cared for the patient and deployed the new MitraClip device. Yes\u2026 This was much, much, much better than an episode of <em>Grey\u2019s Anatomy<\/em>.<\/p>\n<p>Although the MitraClip has yet to receive FDA approval in the United States, Dr. Kar has been using the device to treat mitral valve regurgitation without causing any physical trauma to the patient\u2019s sternum or ribs. As previously discussed, the results of the MitraClip clinical trials have been encouraging.<\/p>\n<p>A few minutes before the procedure began, I was very surprised to see a familiar face enter the cardiac catheterization lab. <a href=\"https:\/\/www.heart-valve-surgery.com\/surgeons\/dr-Alfredo-Trento-Los+Angeles-California.php\">Doctor Alfredo Trento<\/a>, the Chief of Cardiothoracic Surgery at Cedars-Sinai Hospital, quietly assumed a position to left of Dr. Kar.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\" aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/saibal-kar-alfredo-trento-mitraclip.jpg\" alt=\"Dr. Saibal Kar and Dr. Alfredo Trento Perform MitraClip Procedure\" width=\"375\" height=\"250\" \/>Dr. Kar (Cardiologist) and Dr. Trento (Cardiac Surgeon)<br \/>\nWork Side-By-Side During A MitraClip Procedure<\/p>\n<p>&nbsp;<\/p>\n<p>\u201cThis has got to be somewhat unique,\u201d I thought to myself, \u201cGiven the distinct nature of their specialties and some of the skepticism surrounding the MitraClip from the surgeon community, I can not imagine this is common.\u201d (I would later learn that, so far, only a handful of cardiac surgeons have taken a serious clinical interest in this non-invasive procedure used to <a href=\"https:\/\/www.heart-valve-surgery.com\/mitral-valve-regurgitation-symptoms-leaking.php\">treat mitral valve regurgitation<\/a>.)<\/p>\n<p><!--more--><\/p>\n<p>Regardless of their specialties, these cardiac gurus \u2013 Dr. Saibal Kar and Dr. Alfredo Trento \u2013\u00a0 worked seamlessly together.<\/p>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\" aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/alfredo-trento-surgeon-mitraclip.jpg\" alt=\"Alfredo Trento Performing MitraClip Procedure At Cedars Sinai Hosiptal In Los Angeles\" width=\"325\" height=\"488\" \/>Dr. Alfredo Trento, Cardiac Surgeon,<br \/>\nOperating The MitraClip Delivery System<\/p>\n<p>&nbsp;<\/p>\n<p>I\u2019ll be honest\u2026 As an observer, I was relatively clueless to most of the conversations in the catheter lab. There was so much <em>medical data chatter<\/em> going back and forth amongst the medical team &#8211; comprised of cardiologists, surgeons, anesthesiologist and nurses &#8211; that my ears went somewhat numb.<\/p>\n<p>Thankfully, Dr. Kar\u2019s physician assistant, Asma Hussaini, and other visiting cardiologists (including Steve Goldberg, from Kirkland, Washington), helped me understand the key steps of this transformational procedure in laymen\u2019s terms.<\/p>\n<p>For me, there were several highlights of this MitraClip experience:<\/p>\n<ul>\n<li>While the actual MitraClip is tiny, the delivery system by which the MitraClip is passed through the transfemoral vein is quite elaborate and larger than expected.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" src=\"\/Images\/asma-mitraclip.png\" alt=\"\" width=\"262\" height=\"345\" \/><br \/>\nAsma Hussaini Holding The Unopened MitraClip Delivery System<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>The catheter size of the MitraClip guide is 8.6 millimeters in diameter and it is placed via needle puncture into the femoral vein. By comparison, the surgical scar that runs down my sternum is about nine inches, or 228.6 millimeters.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\" aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/mitraclip-catheter-inserted.jpg\" alt=\"MitraClip Catheter Inserted\" width=\"375\" height=\"250\" \/>The Patient&#8217;s Catheter Insertion Site (Groin)<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>A portion of the MitraClip procedure is spent navigating the catheter through the vein to find an optimal area to cross the septum which divides the right and left side of the heart.\u00a0 This assures that the MitraClip will be easily placed in proper position to grasp <a href=\"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/2008\/10\/05\/mitral-leaflet-anatomy-problems-pictures-of-mitral-leaflets\/\">the defective mitral valve leaflets<\/a>.\u00a0 As Dr. Kar explained, \u201cThis is one of the most critical steps in the procedure.\u201d<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\" aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/kar-trento-mitraclip-delivery-system.jpg\" alt=\"Drs. Kar &amp; Trento Insert The MitraClip Delivery System\" width=\"300\" height=\"451\" \/>Dr. Kar, Dr. Trento &amp; Dr. Buch Insert The MitraClip Into The Catheter<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>A small hole must be made in the septum which divides the right and left atrium of the heart to provide the MitraClip access to the diseased mitral valve. No sutures are needed to close this hole as our hearts heal relatively quickly, according to Dr. Goldberg.<\/li>\n<\/ul>\n<ul>\n<li>The clip arms are used to bring the mitral leaflets together creating a double orifice valve. The MitraClip can open-and-close multiple times to ensure the best result.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/mitraclip-tee-catheter.jpg\" alt=\"MitraClip Catheter Positioned Next To TEE\" width=\"350\" height=\"359\" \/>The First MitraClip Is Locked Into Place<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Once the MitraClip is positioned and closed, valve function can be evaluated in real time using two dimensional (2D) and three dimensional (3D) echocardiography. If the mitral regurgitation is eliminated or reduced to \u201cmild\u201d status, the MitraClip is then \u201clocked\u201d into place and separated from the delivery catheters. The MitraClip will then move freely with the mitral leaflets.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/mitraclip-evaluation.jpg\" alt=\"Evaluating The MitraClip After Placement With Echocardography\" width=\"375\" height=\"250\" \/>Dr. Kar and Dr. Trento Evaluate Mitral Regurgitation<br \/>\nAfter Primary MitraClip Closure<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>According to Dr. Saibal Kar, about 30-50% of patients now receive two (2) MitraClips to minimize regurgitation. As you may recall, <a href=\"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/2010\/06\/03\/mitraclip-high-risk-patient-interview-kato-pomer\/\">Kato Pomer, the 92-year old woman I recently interviewed, received two MitraClips<\/a> during her life-saving operation.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/double-mitraclip.jpg\" alt=\"Double MitraClip Placement Under X-Ray\" width=\"375\" height=\"263\" \/>To Minimize Regurgitation, A 2nd MitraClip Is Positioned<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>The MitraClip procedure is covered by some insurance programs. In fact, I heard that a new Medicare code is about to be issued for this non-invasive procedure.<\/li>\n<\/ul>\n<ul>\n<li>The MitraClip is made from cobalt chromium. A polyester fabric coats the clip to promote healing.<\/li>\n<\/ul>\n<ul>\n<li>The MitraClip and delivery system are manufactured in the company\u2019s headquarters in Menlo Park, California.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/www.heart-valve-surgery.com\/Images\/kar-medical-team-mitraclip.jpg\" alt=\"Saibal Kar's Medical Team At Cedars Sinai\" width=\"375\" height=\"255\" \/>Dr. Kar&#8217;s Team &#8211; Noorbibi Gheewalla, CVT (Monitor), Asma Hussaini, PA-C (Physician Assistant), Saibal Kar, M.D., Bret Wertman, M.D. (Interventional Fellow), Omar Dura, M.D. (Anesthesiologist), Mamta Buch, M.D. (Fellow)<\/p>\n<p>&nbsp;<\/p>\n<p>Needless to say, this was an extraordinary experience. I want to thank all of the medical staff at Cedars-Sinai Hospital in Los Angeles, California \u2013 especially Dr. Saibal Kar and Dr. Alfredo Trento.<\/p>\n<p>Most importantly, I just learned that the patient is at home doing very well after the procedure.<\/p>\n<p>Related Links:<\/p>\n<ul>\n<li><a href=\"https:\/\/www.heart-valve-surgery.com\/learning\/mitraclip-indications-gerdisch\/\">Surgeon Q&amp;A: Will The MitraClip Help My Mom?<\/a><\/li>\n<li><a href=\"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/2019\/01\/24\/mitraclip-coapt-patient-story\/\">MitraClip Success: Michelle Is Off The Heart Transplant List<\/a><\/li>\n<li><a href=\"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/2013\/11\/19\/mitraclip-fda-approval\/\">MitraClip FDA Approval: 5 Facts to Know<\/a><\/li>\n<\/ul>\n<p>Keep on tickin!<br \/>\nAdam<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":22961,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[35],"tags":[],"class_list":["post-1343","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-surgeons-clinics"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/posts\/1343","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/comments?post=1343"}],"version-history":[{"count":2,"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/posts\/1343\/revisions"}],"predecessor-version":[{"id":42210,"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/posts\/1343\/revisions\/42210"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/media\/22961"}],"wp:attachment":[{"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/media?parent=1343"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/categories?post=1343"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.heart-valve-surgery.com\/heart-surgery-blog\/wp-json\/wp\/v2\/tags?post=1343"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}