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Heart Valve Replacement And Heart Valve Repair Blog For Patients With Aortic Stenosis, Mitral Regurgitation, Mitral Valve Prolapse, etc.

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Adam Pick - Heart Valves Author & Blogger
Adam Pick
Double Heart Valve Surgery Patient
and Author of The Patient's Guide
To Heart Valve Surgery


> Read My Story Here


Coumadin And Prilosec

Blog Topic: Prilosec; Contraindications Of Coumadin And Prilosec; Drug Complications Following Open Heart Surgery; Side Effects

The other day, I wrote a blog about the Contraindications of Ultram and Coumadin. Since then, I have been bombarded with questions about other potential issues, conflicts and side-effects of Coumadin (Warfarin Sodium).

That said, I will respond to each of your questions over the next few weeks. To advance this topic, I have consulted with a psychiatrist who might be co-blogging with me on this subject. :)

Coumadin And Prilosec

Anyways, one of the questions I recently received was, “Are there any potential issues of taking Coumadin and Prilosec following heart valve replacement?”

First off, it helps if we understand what the drugs Coumadin and Prilosec are and what they were designed to do. As I have previously written, Coumadin is used by heart valve replacement patients following surgery to prevent blood-clots on their mechanical heart valve replacements.

Prilosec, on the other hand, is used to treat symptoms of GERD, or gastroesophageal reflux disease, and other conditions resulting from excess stomach acid.

(FYI, my cardiologist put me on Prilosec following my aortic and pulmonary valve replacement. But, you should know that I was not on Coumadin. Since I did not choose a mechanical valve, I am not required to use Coumadin. My cardiologist put me on Prilosec to help mitigate stomach upset due to the pain medication - Vicodin - I was on.)

Now, that we know a little bit about Coumadin and Prilosec, we can better understand any potential issues for heart valve replacement patients taking both Coumadin and Prilosec.

My research indicates that - similar to Ultram and Coumadin - there MAY BE issues when taking both Coumadin and Prilosec at the same time. According to Drugs.com, Coumadin is referenced as a drug that will affect Prilosec users. Unfortunatley, the website, does not share much more information about the potential contraindications or side effects.

I went to a number of other medical sites to learn more about the potential interactions between Coumadin and Prilosec and found no additional information. That said, I am going to ask a few doctors to learn if they are aware of any potential issues or side-effects of taking Coumadin and Prilosec simultaneously following heart valve surgery.

If you know anything, please feel free to leave a comment below!

I hope this helps you better understand the potential drug interactions between Coumadin and Prilosec.

Keep on tickin,

Adam

Adam Pick is the author of The Patient’s Guide To Heart Valve Surgery, a unique book which integrates the clinical facts of heart valve surgery with the personal experiences of an actual heart valve surgery patient. This special book was designed to minimize stress and enhance the patient’s recovery. To learn more about Adam’s heart valve surgery book, click here.

>> Additional Blogs About Heart Valve Surgery:


4 Responses to “Coumadin And Prilosec”

  1. Robert Light MD Says:

    Adam,

    Prilosec (omeprazole) may inhibit hepatic metabolsim of coumadin (warfarin) and cause an increase in INR and thus an increased chance of bleeding. It is recommended to keep the Prilosec dose to less than 20 mgs a day.

    Let me know if you have any other questions,

    Robert Light, MD
    Diplomat of the American Board of Psychiatry and Neurology

  2. Dr. Robert Light To Provide Medical Insight On Heart Surgery Blog Says:

    […] Dr. Robert Light has already begun sharing his thoughts on prior blogs including Coumadin and Prilosec as well as Contraindications of Ultram and Coumadin. […]

  3. Coumadin Medication Interactions Says:

    […] That said, this blog is also starting to answer some questions about Coumadin medication interactions with other popular drugs - including Coumadin and Prilosec and Ultram and Coumadin. […]

  4. Wilmer Brown Says:

    I had a mechanical Valve implanted on 2 June 08. Am taking Coumadin and Prilosec. Have not noticed any problems yet.

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